Understand the benefits of simple administration that meet your patients’ needs
Simple administration and adherence
When selecting a regimen for your patients, components and configuration are important. Simple administration, reducing side effects, accessibility of medication, and maintaining an uninterrupted supply of ART medication can help patients overcome potential adherence barriers. Prescribing a regimen with once-daily dosing can help minimize the risk of resistance by promoting adherence through a lower pill burden.1
Consider each of your patients’ needs related to treatment administration.
An administration approach tailored to each patient’s activities is associated with higher levels of adherence. Regimens that support adherence may bear the following characteristics1:
According to the DHHS guidelines, once-daily dosing can help minimize the risk of resistance by promoting adherence through a lower pill burden.1
Potential benefits of simplified administration:
Low pill burden1
Lower dose frequency1
Decreased healthcare costs2
Fewer prescriptions needed3
Simple administration can help promote adherence, which may reduce the risk of drug resistance.1
ART, antiretroviral therapy; DHHS, US Department of Health and Human Services.
- Panel on Antiretroviral Guidelines for Adults and Adolescents. Guidelines for the use of antiretroviral agents in adults and adolescents with HIV. Department of Health and Human Services. Updated January 20, 2022. Accessed January 31, 2022. https://clinicalinfo.hiv.gov/sites/default/files/guidelines/documents/guidelines-adult-adolescent-arv.pdf
- Vitoria M, Ford N, Doherty M, Flener C. Simplification of antiretroviral therapy: a necessary step in the public health response to HIV/AIDS in resource-limited settings. Antivir Ther. 2014;19(suppl 3):31-37.
- Hemmige V, Flash C, Carter J, Giordano T, Zerai T. Single tablet HIV regimens facilitate virologic suppression and retention in care among treatment naïve patients. AIDS Care. 2018;30(8):1017-1024.